Biochemistry & Genetics: Pretest Self-Assessment & Review by Golder Wilson

By Golder Wilson

PreTest is the nearest you will get to seeing the USMLE Step 1 earlier than you are taking it!

500 USMLE-style questions and answers!

Great for path evaluate and the USMLE Step 1, PreTest asks the best questions so you’ll be aware of the precise solutions. You’ll locate 500 clinical-vignette variety questions and solutions besides entire motives of right and fallacious solutions. The content material has been reviewed by means of scholars who lately handed their tests, so that you be aware of you're learning the main proper and updated fabric attainable. No different learn consultant ambitions what you really want to grasp so that it will go like PreTest!

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Additional info for Biochemistry & Genetics: Pretest Self-Assessment & Review

Sample text

10. The answer is c. (Murray, pp 412–434. Scriver, pp 3–45. Sack, pp 3–29. ) Despite the great length of the chromosomes of eukaryotic DNA, the actual replication time is only minutes. This is because eukaryotic DNA is replicated bidirectionally from many points of origin. The hundreds of initiation sites for DNA replication on chromosomes share a consensus sequence called an autonomous replication sequence (ARS). Thus, while the process of DNA replication in mammals is similar to that in bacteria, with DNA polymerases of similar optimal temperatures and speed, the many replication forks allow for a rapid synthesis of chromosomal DNA.

The genetic code (codon assignments in messenger RNA. (Reproduced, with permission, from Murray RK, Granner DK, Mayes PA, Rodwell VW: Harper’s Biochemistry, 25/e. qxd 11/14/01 10:37 AM Page 49 Gene Expression Answers 49 34. The answer is d. (Murray, pp 452–467. Scriver, pp 3–45. Sack, pp 1–40. ) Sickle cell anemia (141900) is an autosomal recessive hemoglobinopathy with an incidence of 1 in 500 African American births. It is caused by a single-nucleotide substitution in codon 6 of the β-globin gene.

Defective structure of the signal recognition particles e. qxd 11/14/01 10:37 AM Page 48 Gene Expression Answers 33. The answer is b. (Murray, pp 452–467. Scriver, pp 3–45. Sack, pp 1–40. ) The “genetic code” uses three-nucleotide “words,” or codons, to specify the 20 different amino acids (see the chart below). There are 64 different three–base pair codons (three positions with four possible nucleotides at each). , different codons can specify the same amino acid. Three codons are reserved as “stop” signals that result in peptide chain termination.

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